Born in Awgbu Town, in Orumba North, Anambra state, Ezeajughi had his primary, secondary and tertiary education in Anambra.

He attended Aguata High School, Aguata, and Nnamdi Azikiwe University, Awka, where he studied Applied Microbiology.

Ezeajughi was actively involved in student union politics, representing the departmental students union body. Currently,
Ernest Ezeajughi is the 1st black Mayor of London Borough of Brent

After graduation in 1998 and completion of his National Youth Service Corps (NYSC), he worked briefly in the private family business – Koval Linkworld Agencies Ltd – before migrating to England to join his wife.

In England, Ezeajughi obtained a Master’s degree in Science (M.Sc) from the prestigious Kings College, London.

A scientist by profession, he worked with Medicine and Healthcare Products Regulatory Agency (MHRA).

Ezeajughi was one of the founding fathers of a major Nigerian political party, the All Progressives Grand Alliance (APGA) UK Chapter and was the chairman in 2010-2012.

He later joined UK politics and soon became a strong member of the Labour Party.